Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ins2  insulin II   (Synonyms: Ins-2, InsII, Mody, Mody4)
Results	Reference
1	J:121934 Arnaud-Dabernat S, Kritzik M, Kayali AG, Zhang YQ, Liu G, Ungles C, Sarvetnick N, FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells. Diabetes. 2007 Jan;56(1):96-106
1	J:98803 Collombat P, Hecksher-Sorensen J, Broccoli V, Krull J, Ponte I, Mundiger T, Smith J, Gruss P, Serup P, Mansouri A, The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the {alpha}- and {beta}-cell lineages in the mouse endocrine pancreas. Development. 2005 Jul;132(13):2969-80
1*	J:113424 Dichmann DS, Yassin H, Serup P, Analysis of pancreatic endocrine development in GDF11-deficient mice. Dev Dyn. 2006 Nov;235(11):3016-25
1	J:147261 Gesina E, Blondeau B, Milet A, Le Nin I, Duchene B, Czernichow P, Scharfmann R, Tronche F, Breant B, Glucocorticoid signalling affects pancreatic development through both direct and indirect effects. Diabetologia. 2006 Dec;49(12):2939-47
1	J:296539 Helman A, Cangelosi AL, Davis JC, Pham Q, Rothman A, Faust AL, Straubhaar JR, Sabatini DM, Melton DA, A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion. Cell Metab. 2020 May 5;31(5):1004-1016.e5
1	J:186674 Hoffmann A, Spengler D, Transient neonatal diabetes mellitus gene Zac1 impairs insulin secretion in mice through Rasgrf1. Mol Cell Biol. 2012 Jul;32(13):2549-60
1*	J:76349 Hussain MA, Miller CP, Habener JF, Brn-4 Transcription Factor Expression Targeted to the Early Developing Mouse Pancreas Induces Ectopic Glucagon Gene Expression in Insulin-producing beta Cells. J Biol Chem. 2002 May 3;277(18):16028-32
1	J:51571 Krapp A, Knofler M, Ledermann B, Burki K, Berney C, Zoerkler N, Hagenbuchle O, Wellauer PK, The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev. 1998 Dec 1;12(23):3752-63
1	J:162502 Mwangi SM, Usta Y, Raja SM, Anitha M, Chandrasekharan B, Parsadanian A, Sitaraman SV, Srinivasan S, Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and beta-cell proliferation in the developing mouse pancreas. Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G283-92
1*	J:22505 Nissinen MJ, Panula P, Developmental patterns of histamine-like immunoreactivity in the mouse. J Histochem Cytochem. 1995 Feb;43(2):211-27
1	J:192805 Nyren R, Chang CL, Lindstrom P, Barmina A, Vorrsjo E, Ali Y, Juntti-Berggren L, Bensadoun A, Young SG, Olivecrona T, Olivecrona G, Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency. BMC Physiol. 2012;12:14
1	J:183924 Perez-Armendariz EM, Cruz-Miguel L, Coronel-Cruz C, Esparza-Aguilar M, Pinzon-Estrada E, Rancano-Camacho E, Zacarias-Climaco G, Olivares PF, Espinosa AM, Becker I, Saez JC, Berumen J, Perez-Palacios G, Connexin 36 is Expressed in Beta and Connexins 26 and 32 in Acinar Cells at the End of the Secondary Transition of Mouse Pancreatic Development and Increase During Fetal and Perinatal Life. Anat Rec (Hoboken). 2012 Jun;295(6):980-90
1	J:282308 Romer AI, Singer RA, Sui L, Egli D, Sussel L, Murine Perinatal beta-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1. Diabetes. 2019 Dec;68(12):2259-2271
1	J:129652 Vuguin PM, Kedees MH, Cui L, Guz Y, Gelling RW, Nejathaim M, Charron MJ, Teitelman G, Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation. Endocrinology. 2006 Sep;147(9):3995-4006
1	J:57319 Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL, White MF, Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. Nat Genet. 1999 Sep;23(1):32-40
1	J:180955 Xia F, Dohi T, Martin NM, Raskett CM, Liu Q, Altieri DC, Essential role of the small GTPase Ran in postnatal pancreatic islet development. PLoS One. 2011;6(11):e27879
1	J:91887 Zhang YQ, Cleary MM, Si Y, Liu G, Eto Y, Kritzik M, Dabernat S, Kayali AG, Sarvetnick N, Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells. Diabetes. 2004 Aug;53(8):2024-33